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目的 研究急性脑梗死患者血压变化规律及其与神经功能损伤的关系。方法 通过动态血压监护 ,探讨急性脑梗死患者血压变化规律及其对神经功能损伤的影响。结果 急性脑梗死发病后血压先迅速升高 ,维持 3d左右后自发回落 ,至第 7日基本稳定。约 3 8%的急性脑梗死患者血压回落明显 ,其中 5 6%伴发神经功能损伤进展。发病年龄高、初始神经功能损伤严重和大剂量应用甘露醇、硫酸镁、硝酸甘油与血压降低有关。结论 急性脑梗死患者血压呈先增高再回落的自发趋势 ,血压过度降低可造成神经功能损伤进展
Objective To study the changes of blood pressure and its relationship with neurological impairment in patients with acute cerebral infarction. Methods By means of ambulatory blood pressure monitoring, we investigated the changes of blood pressure and its effect on neurological impairment in patients with acute cerebral infarction. Results After the onset of acute cerebral infarction, the blood pressure increased rapidly at first and then spontaneously dropped after about 3d, and basically stabilized on the 7th. About 38% of patients with acute cerebral infarction blood pressure dropped significantly, of which 56% with progressive neurological injury. High age of onset, severe initial neurological damage and high doses of mannitol, magnesium sulfate, nitroglycerin and decreased blood pressure. Conclusions The blood pressure of patients with acute cerebral infarction presents a spontaneous trend of first rising and then falling back. Excessive blood pressure can lead to the progression of neurological impairment