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目的探索血清肿瘤标志物在结直肠癌患者预后评估中的临床价值。方法对结直肠癌患者肿瘤标志物进行测定,并采用拟合优度检验方法筛选能够预测复发的肿瘤标志物组合。结果单项检测肿瘤标志物敏感性较差,CEA、CA19-9、CA24-2阳性水平影响复发。最佳预测预后组合方案为CEA、CA19-9。结论血清肿瘤标志物联合检测可以作为结直肠癌患者预后评价的依据。
Objective To explore the clinical value of serum tumor markers in the prognosis evaluation of patients with colorectal cancer. Methods Tumor markers in patients with colorectal cancer were determined, and the goodness of fit test was used to screen the tumor marker combinations that could predict the recurrence. Results The single detection of tumor markers was less sensitive, and the positive rates of CEA, CA19-9 and CA24-2 affected the relapse. The best combination of prognosis prognosis for the CEA, CA19-9. Conclusion Combined detection of serum tumor markers can be used as a basis for prognosis evaluation of patients with colorectal cancer.