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患者男性53岁,飞行人员。1963年～1973年常感上腹部隐疼、腹胀。1973年3月起出现双眼睑及双下肢浮肿,半年后因髋关节痛住院。当时血色素137克/L(13.7克/dl),肝、肾功能及心脏检查未见异常。1974年初并出现面黄,下肢酸软,纳差,头晕,睡眠不佳。同年4月发现血色素80克/L,红细胞3.2×10~(12)L,白细胞3.2×10~9/L,血小板134×10~9/L。1973～1978年期间住院五次,后四次曾作胃镜检查,胃粘膜病理均为慢性萎缩性胃炎,腺体上皮轻度不典型增生,每次入院后试餐前后胃液游离酸均为零,出院前则均有不同程度上升,试餐前平均上升22.7单位,试餐后上升41.7单位。血色素平均升高34克/L。
Male 53 years old, pilot. 1963 ~ 1973 often sense of upper abdomen pain, abdominal distension. Occurred in March 1973 double eyelid and lower extremity edema, six months after hospitalization for hip pain. At that time hemoglobin 137 g / L (13.7 g / dl), liver and kidney function and cardiac examination showed no abnormalities. In early 1974 and appeared yellow, lower extremity soreness, anorexia, dizziness, poor sleep. In the same year in April found that hemoglobin 80 g / L, red blood cells 3.2 × 10 ~ (12) L, leukocytes 3.2 × 10 ~ 9 / L, platelet 134 × 10 ~ 9 / L. Hospitalized from 1973 to 1978 five times, after four times had gastroscopy, gastric mucosal pathology are chronic atrophic gastritis, glandular epithelial mild atypical hyperplasia, gastric juice free acid after each meal were zero, Before discharge, they all had different degrees of increase, with an average increase of 22.7 units before meals and 41.7 units after meals. Hemoglobin average increased 34 g / L.