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为了证实日本血液透析病人和医院透析工作人员中丙型肝炎病毒(HCV)感染率,作者对上述人员应用酶联免疫吸附法(ELISA)测定抗-C100、抗 KCL-163(HCV 非结构蛋白)和抗-JCC(假设 HCV 核基因转移产物)。病人和方法对489例(男275、女214)病人进行研究。年龄20～91岁(平均56.8)岁,均因慢性肾功能衰竭而接受血液透析。平均透析5.2年。第2组152名(男16,女136)透析工作人员,年龄18～57(平均30.3)岁。另在115771名健康供血者(男66235,女49536)和另外919名供血者(男529.女390)采血作对照。测定抗-C100抗体、抗-KCL和抗-JCC。结果 489例病人中,100例(20.4%)抗-C100,107例(21.9%)抗-KCL 和168例
To validate the rate of hepatitis C virus (HCV) infection among hemodialysis patients and dialysis workers in Japan, the authors tested anti-C100, anti-KCL-163 (HCV nonstructural proteins) And anti-JCC (assuming HCV nuclear gene transfer product). Patients and Methods 489 patients (275, 214) were studied. Aged 20 to 91 years (mean 56.8) years of age, all due to chronic renal failure and hemodialysis. Average dialysis 5.2 years. Group 2 152 (male 16, female 136) dialysis staff, aged 18 to 57 (average 30.3) years of age. Blood was also collected from 115,771 healthy donors (male 66235, female 49536) and another 919 donors (male 529. female 390). Anti-C1OO antibodies, anti-KCL and anti-JCC were determined. Results Of the 489 patients, 100 (20.4%) were resistant to -C100, 107 (21.9%) were anti-KCL and 168