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目的对启东2001~2007年全人群宫颈癌登记病例进行生存率分析,为预后评价及防治提供依据。方法 241例登记病例的生存(死亡)情况随访截止于2009年12月31日,用SURV3.01软件计算观察生存率(OS)及相对生存率(RS)。结果宫颈癌1,3,5年OS分别为64.32%、52.62%和50.69%;1,3,5年RS分别为65.34%、55.18%和54.99%。15~34岁、35~44岁、45~54岁、55~64岁、65~74岁及75岁以上各年龄组的5年OS分别为73.68%、70.20%、63.19%、39.64%、16.09%和20.00%;5年RS分别为73.86%、70.79%、64.51%、41.29%、18.42%和36.37%。年轻宫颈癌患者有较高的相对生存率,各年龄组生存率相比差异有显著性(P<0.05)。启东2001~2007年宫颈癌5年OS、RS比1976~2000年各时期有了较大的提高。结论启东市20世纪70年代以来全人群宫颈癌登记病例的总体预后已有长足的进步,但与国外发达国家相比尚有差距。宫颈癌的防治任重道远。
Objective To analyze the survival rate of all the registered cases of cervical cancer in Qidong from 2001 to 2007, and provide the basis for prognosis evaluation and prevention. Methods Survival (death) of 241 enrolled cases was followed up on December 31, 2009. Survival (OS) and relative survival (RS) were calculated by SURV3.01 software. Results The 1, 3, 5-year OS rates of cervical cancer were 64.32%, 52.62% and 50.69% respectively. The RSDs of 1, 3 and 5 years were 65.34%, 55.18% and 54.99% respectively. The 5-year OS of 15-34, 35-44, 45-54, 55-64, 65-74, and 75-year-old were 73.68%, 70.20%, 63.19%, 39.64%, 16.09 % And 20.00%, respectively. The 5-year RS was 73.86%, 70.79%, 64.51%, 41.29%, 18.42% and 36.37%, respectively. Young patients with cervical cancer have a higher relative survival rate, survival rates in all age groups were significantly different (P <0.05). Qidong cervical cancer in 2001 ~ 2007 5-year OS, RS than 1976 to 2000 have been greatly improved. Conclusion The overall prognosis of all cases of cervical cancer registered in Qidong has been greatly improved since the 1970s, but there is still a gap compared with other developed countries. Prevention and treatment of cervical cancer long way to go.