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目的了解2002-2014年浦东新区居民大肠癌死亡流行病学特点及其趋势,为制定相关的干预措施提供依据。方法根据2002-2014年浦东新区户籍死因监测数据库,采用死亡率、标化死亡率、年度变化百分比(APC)、潜在减寿年数(PYLL)、平均减寿年数(AYLL)等指标对大肠癌死亡情况进行分析。结果 2002-2014年浦东新区大肠癌粗死亡率为21.64/10万,标化死亡率为9.84/10万。大肠癌粗死亡率呈现逐年上升的趋势(APC=3.99%,Z=-17.207,P<0.001),标化死亡率无明显变化趋势(APC=0.34%,Z=-1.270,P=0.230)。男性大肠癌死亡率高于女性(Z=8.286,P<0.001)。浦东新区大肠癌PYLL为32 137年,PYLL率为0.93‰,AYLL为4.31年/人。PYLL呈现逐年上升的趋势(APC=2.26%,Z=-2.920,P=0.014)。结论浦东新区大肠癌粗死亡率及PYLL呈现逐年上升的趋势,提示应加强针对大肠癌的防控措施,深入推进上海市大肠癌筛查工作。
Objective To understand the epidemiological characteristics and trends of death from colorectal cancer in residents of Pudong New Area from 2002 to 2014 and provide the basis for making relevant interventions. Methods According to the monitoring database of household registration and death in Pudong New Area from 2002 to 2014, the mortality of colorectal cancer was calculated using the indicators of mortality, standardized mortality, annual change percentage (APC), potential years of life lost (PYLL), and average life expectancy (AYLL) Situation analysis. Results In 2002-2014, the crude mortality rate of colorectal cancer in Pudong New District was 21.64 / 100000, and the standardized mortality rate was 9.84 / 100000. The crude mortality of colorectal cancer showed a trend of increasing year by year (APC = 3.99%, Z = -17.207, P <0.001). There was no significant change in the standard mortality (APC = 0.34%, Z = -1.270, P = 0.230). Mortality in men with colorectal cancer was higher than in women (Z = 8.286, P <0.001). The PYLL of Pudong New Area was 32 137 years, the PYLL rate was 0.93 ‰, and the AYLL was 4.31 years / person. PYLL showed a trend of increasing year by year (APC = 2.26%, Z = -2.920, P = 0.014). Conclusion The crude mortality rate and PYLL in Pudong New Area have shown an upward trend year by year, suggesting that we should strengthen the prevention and control measures against colorectal cancer and further promote the screening of colorectal cancer in Shanghai.