缓慢浸润方式与恶性卵巢畸胎瘤预后不良的病例报道

• 作 者: SpannuthW.A Rocconi R.P Kirby T.O 侯巍
• 机 构: Division of Gynecologic Oncology Department of Obstetrics and Gynecology University of Alabama at B
• 出 处: 世界核心医学期刊文摘(妇产科学分册)
• 发表日期: 2005年10期
• 关键词: 卵巢畸胎瘤 成熟畸胎瘤 左侧卵巢 病例 鳞状细胞癌 辅助化疗 肿瘤浸润 临床分期 病理诊断 疾病预后

Background. Although mature cystic teratoma is the most common tumor of the ovary, squamous cell carcinoma arising from a mature teratoma is a rare event. Prognosis depends on clinical stage, grade, and recently described mode of tumor infiltration. Case. This case involves a 52- year- old woman with stage II squamous cell carcinoma arising in a mature cystic teratoma of the left ovary. Final pathology demonstrated poorly differentiated squamous cell carcinoma with gamma mode of tumor infiltration. The patient completed adjuvant chemotherapy and subsequently died of progressive disease. Conclusion. Squamous cell carcinoma arising from a benign cystic teratoma is a rare event. Studies have shown stage, grade, and mode of infiltration to be predictors of recurrence and prognosis. This case supports the growing evidence linking the mode of tumor infiltration with overall prognosis of survival.

Background. Although mature cystic teratoma is the most common tumor of the ovary, squamous cell carcinoma arising from a mature teratoma is a rare event. Prognosis depends on clinical stage, grade, and recently described mode of tumor infiltration. Case. This case involves a 52- year-old woman with stage II squamous cell carcinoma arising in a mature cystic teratoma of the left ovary. Final pathology demonstrated poorly differentiated squamous cell carcinoma with gamma mode of tumor infiltration. The patient completed adjuvant chemotherapy and succeeding died of progressive disease. Studies have shown stage, grade, and mode of infiltration to be predictors of recurrence and prognosis. This case supports the growing evidence linking the mode of tumor infiltration with overall prognosis of survival.