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1985年4~7月,在缅甸仰光以北的Thar rawaddy Civil医院,对62例恶性疟成年患者进行观察。当地是疟疾终年高度流行区,已证实恶性疟原虫存在氯喹抗性。患者均经有关测定,表明于住院前未用过抗疟药;按年龄、性别和并发症配对分为2组。蒿甲醚组中男性23例,女性8例;年龄均≥48岁,平均年龄为31±14岁;平均体重44.4±6.8kg;无性体为300000±410000个/mm~3。奎宁组中男性22例,女性9例;平均年龄为32±15岁;平均体重43.6±6.9kg;无性体为360000±640000个/mm~3。上述各项,两组间均无显著性差异
From April to July 1985, 62 adult patients with falciparum malaria were observed at Thar Rawaddy Civil Hospital, north of Yangon, Myanmar. The local area is a year-long endemic area of malaria, and chloroquine resistance has been confirmed in Plasmodium falciparum. Patients were determined by the relevant tests showed that before the hospital did not use antimalarial drugs; by age, gender and complications paired into two groups. In the artemether group, there were 23 males and 8 females. All were ≥48 years old, with an average age of 31 ± 14 years. The mean body weight was 44.4 ± 6.8 kg. The number of sepsis was 300 000 ± 41 000 / mm 3. In the quinine group, there were 22 males and 9 females, with an average age of 32 ± 15 years; mean body weight of 43.6 ± 6.9 kg; and asexual size of 360000 ± 640000 / mm 3. The above items, no significant difference between the two groups