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目的本文对复治的多耐药(MDR)肺结核病人产生MDR的临床原因、耐药种类及住院后三组不同治疗方案的疗效进行探讨。方法利用临床资料总结分析和讨论。结果224例复治MDR肺结核产生多耐药主要原因是初治期间不满规定疗程即停药及间断不规则用药,二者共占84.8%。耐药种类主要是耐3种药物以上,以HRS为主。本文还对多耐药肺结核的治疗进行了观察与分析。结论抓好初治病例的治疗和管理是防止MDR产生的关键。对MDR肺结核病人治疗选择氧氟沙星与其它敏感的抗结核药物联合应用疗效较满意。//
Objective To investigate the clinical causes, the types of resistance and the efficacy of three different treatment regimens after multidrug-resistant (MDR) pulmonary tuberculosis patients receiving retreatment. Methods The clinical data summary analysis and discussion. Results 224 cases of multidrug-resistant MDR pulmonary tuberculosis multi-drug resistance is mainly due to dissatisfaction with the prescribed treatment during the initial treatment discontinuation and discontinuous medication, the two accounted for a total of 84.8%. Resistance types are mainly resistant to more than 3 drugs, mainly HRS. The article also observed and analyzed the treatment of multidrug-resistant tuberculosis. Conclusions Good treatment and management of early treatment cases is the key to prevent MDR. Of MDR tuberculosis patients choose ofloxacin and other sensitive antituberculosis drugs combined with more satisfactory results. //