论文部分内容阅读
突触可塑性是指由各种突触前和突触后机制介导的可伴随形态变化而变化的突触功效,神经树突和轴突在多种神经因子作用和多种受体参与的信息传递和反馈调解下,致使神经突触的可塑性与调控发生变化,致使神经环路重构。本文将集中探讨神经胶质细胞,神经因子等不同受体的运输、传递、反馈及作用靶点等对突触可塑性的调控机制,理清与神经和精神疾病的发病机制、病理过程及神经递质受体的调节功能对突触可塑性的影响作用。为探索和研究新型药物,针对靶点治疗,提高脑的认知能力和开发大脑的潜能等方面引导思路方向提供依据。
Synaptic plasticity refers to synaptic efficacy mediated by various presynaptic and post-synaptic mechanisms that can change with morphological changes, information on the role of neuronal dendrites and axons in a variety of neurological factors and the various receptors involved Transmission and feedback mediation, resulting in synaptic plasticity and changes in regulation, resulting in neural circuit remodeling. This article will focus on glial cells, neurotransmitters and other receptors of transport, transmission, feedback and target of synaptic plasticity and other regulatory mechanisms, to clarify the pathogenesis of neurological and psychiatric disorders, pathological processes and neurotransmitters Effect of Regulatory Function of Receptors on Synaptic Plasticity. In order to explore and research new drugs, target therapy, improve brain cognitive ability and the potential to develop the brain to provide the basis for guiding ideas.