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急性肝缺血再灌注后,损伤肝细胞的功能和结构并不很快恢复,甚至加重,其主要原因之一是再灌注后肝脏微循环的“无血再流现象”,或肝脏微循环衰竭。目前对这一现象尚无满意解释。本文简要阐述肝缺血再灌注后肝脏微循环障碍的发生机理及其肝脏微循环障碍在肝缺血损伤中的作用。
After acute hepatic ischemia / reperfusion, the function and structure of injured liver cells do not recover or even rapidly increase, one of the main reasons is the “no-rebreath phenomenon” of liver microcirculation after reperfusion or the failure of hepatic microcirculation . At present there is no satisfactory explanation for this phenomenon. This article briefly describes the mechanism of hepatic microcirculation disturbance after hepatic ischemia-reperfusion and the role of hepatic microcirculation disturbance in hepatic ischemic injury.