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时间肺活量等测验,虽对阻塞性呼吸道疾患的诊断有帮助,但不足以反映细支气管的功能损害。最大呼气中段流速测验和不同频率的肺顺应性等测验,虽能反映一些细支气管情况,但前者不够敏感,后者需要很复杂的设备。近年来闭合肺容量测验操作比较容易,可以检查细支气管功能改变。本文报告一组不吸烟正常人的闭合肺容量测验结果。闭合肺容量测验的原理,是利用从残气基础上吸气后通气分布的不平衡性。操作时需要一种标记气体,最初是用氙~(133),也可用其他惰性气体如氮、氩、或氦。本文用的是氙~(133)。被测者坐位,作最大呼气至
Time spirometry and other tests, although the diagnosis of obstructive airway disease helpful, but not enough to reflect the functional bronchioles damage. The maximal expiratory flow rate test and lung compliance tests at different frequencies reflect some bronchioles, but the former is less sensitive and the latter requires more complex equipment. In recent years, closed lung volume test operation is relatively easy, you can check the bronchial function changes. This article reports the results of a closed lung capacity test for a group of non-smokers. The principle of closed lung volume test is to use the imbalance of ventilation distribution after inhalation based on residual gas. The operation requires a labeled gas, initially xenon ~ (133), but also other inert gases such as nitrogen, argon, or helium. This article uses xenon ~ (133). Subjects were sitting for the maximum exhale to