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目的了解内蒙古自治区<15岁儿童格林巴利综合征(Guillian-BarréSyndrome,GBS)的流行病学特征,为GBS防控提供科学依据。方法对内蒙古自治区2005-2014年报告的214例<15岁儿童GBS病例进行描述性分析。结果内蒙古自治区<15岁儿童GBS年平均报告发病率为0.49/10万,病例呈散发状态;发病高峰出现在6~10月;1~4岁组居多,占病例总数的44.39%;男性多于女性,男女性别比为1.46∶1;从13例病例中分离到肠道病毒,肠道病毒分离率为6.07%;25.23%的病例在60 d随访时有残留麻痹。结论内蒙古自治区<15岁儿童GBS在夏秋季高发,发病以小年龄组居多,一定比例的病例有残留麻痹。应加强对GBS病例的管理,降低致残率。
Objective To understand the epidemiological characteristics of Guillian-Barre Syndrome (GBS) in children <15 years old in Inner Mongolia Autonomous Region and to provide a scientific basis for prevention and control of GBS. Methods A descriptive analysis of GBS cases in 214 children <15 years of age reported by Inner Mongolia Autonomous Region in 2005-2014. Results The average annual incidence of GBS in children <15 years old in Inner Mongolia Autonomous Region was 0.49 / 100000, the cases were sporadic; the peak appeared in 6 ~ 10 months; the majority of children aged 1 ~ 4 accounted for 44.39% of the total cases; Female, sex ratio of male to female was 1.46:1. Enterovirus was isolated from 13 cases, the enterovirus isolation rate was 6.07%, and 25.23% cases were paralyzed after 60 days follow-up. Conclusion GBS in children <15 years old in Inner Mongolia Autonomous Region is high in summer and autumn. The incidence of GBS is mostly in the younger age group. A certain proportion of cases have residual paralysis. Should strengthen the management of GBS cases, reduce the morbidity.