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实验用24只杂种狗进行。其中12只麻醉开胸狗测定了血流动力学某些指标包括血压,心率,主动脉根部、颈总动脉、肾动脉和股动脉的血流量在三小时内的正常波动范围。另麻醉开胸狗12只,静注阿托品、东莨菪碱和山莨菪碱2、4、8和16mg/kg,较大剂量引起血压下降、心率减慢、心输出量增加、肾动脉血流量减少、总外周血管阻力和颈总动脉及股动脉血管阻力降低。三药相比,以阿托品作用最强,其次为山莨菪碱,而东莨菪碱作用最弱。
Experiment with 24 hybrid dogs. Twelve of these anaesthetized thoracodorsa measured hemodynamic parameters such as blood pressure, heart rate, blood flow in the aortic root, common carotid, renal, and femoral arteries within the normal range of three hours. The other 12 anesthetized thoracotomy dogs, intravenous injection of atropine, scopolamine and anisodamine 2,4,8 and 16mg / kg, higher doses caused by blood pressure, heart rate, cardiac output increased renal blood flow decreased, total Peripheral vascular resistance and carotid and femoral artery vascular resistance decreased. Compared with the three drugs, the strongest role of atropine, followed by anisodamine, and scopolamine weakest.