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术后认知功能障碍(POCD)是手术患者尤其是老年手术患者麻醉和术后认知的损害,其发生机制不明确。随着人口老龄化的加速及医疗技术的不断更新,老年患者进行手术的机会大大增加,且大多数老年患者会在全身麻醉下进行手术。随着麻醉深度监测技术的发展,人们对手术患者在不同麻醉深度下POCD的发生有了更多的研究与认识,但研究结果并不一致。了解不同麻醉深度下POCD的发生情况及其作用机制,可为POCD的防治提供更多的理论依据。“,”Postoperative cognitive dysfunction(POCD) is described as cognitive deficits after anesthesia and surgery,especially in elderly patients.The pathogenesis of POCD is not yet entirely clear.With the accel-eration of the aging of population and clinical technology upgrading,the opportunity for surgery in elderly patients is greatly increased,and most patients will undergo surgery under general anesthesia.With the pro-gress of the monitoring technology of anesthesia depth,there are more studies and understanding of POCD under different anesthesia depths but the results of the study are not consistent .Understanding the occurrence of POCD under different depths of anesthesia and its mechanisms, can provide more theoretical basis for POCD prevention and treatment.