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外分泌胰腺癌侵袭性强,很早即有局部淋巴结转移,确诊时仅有10%～15%的病人可行手术切除,由于局部浸润,早期淋巴转移和血性转移,其确诊后1年生存率12%,5年生存率小于4%[1],手术以后的5年生存率也在12%～20%之间[2],是消化系统肿瘤中预后最差的一种。实体肿瘤的生长和转移有赖于
Exocrine pancreatic cancer is aggressive and has local lymph node metastasis very early. Only 10% to 15% of patients diagnosed with this disease are available for surgical resection. Due to local infiltration, early lymphatic metastasis and hematogenous metastasis, the 1-year survival rate after diagnosis is 12% , 5-year survival rate is less than 4% [1], 5-year survival rate after surgery is also between 12% to 20% [2], is the worst prognosis of digestive system tumors. Solid tumor growth and metastasis depends on