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目的观察兰索拉唑三联疗法对幽门螺旋杆菌(HP)阳性的消化性溃疡的疗效。方法将符合条件的患者随机分为2组,治疗组应用兰索拉唑,克拉霉素,阿莫西林三联治疗1周,之后兰索拉唑3周疗法。对照组应用奥美拉唑,甲硝唑,阿莫西林三联1周,之后奥美拉唑3周疗法。疗程结束1个月后进行胃镜和HP检查。结果治疗组与对照组溃疡愈合率分别为93.3%和90%,,HP根除率分别为90%和73.3%。结论兰索拉唑三联疗法确切,症状缓解迅速,依从性好。
Objective To observe the efficacy of lansoprazole triple therapy on Helicobacter pylori (HP) -positive peptic ulcer. Methods The eligible patients were randomly divided into two groups, the treatment group lansoprazole, clarithromycin, amoxicillin triple treatment for 1 week, followed by lansoprazole 3 weeks therapy. The control group omeprazole, metronidazole, amoxicillin triple for 1 week, followed by omeprazole for 3 weeks therapy. Endoscopy 1 month after the endoscopy and HP examination. Results The healing rates of ulcer in treatment group and control group were 93.3% and 90% respectively, and the eradication rates of HP were 90% and 73.3% respectively. Conclusion Lansoprazole triple therapy is accurate, rapid response to symptoms, good compliance.