青霉素类抗生素皮试药物选用的临床研究

• 作 者: 余佳 陈琼枝 刘瑛 樊慧 贾天贵 陈圣堂 庞福佳 昝炜 张蓉 左丽明
• 机 构: 四川省广元市中医院,
• 出 处: 中国现代药物应用
• 发表日期: 2010年21期
• 关键词: 青霉素类抗生素 皮试药物 选用 研究

目的探讨青霉素类抗生素使用前的皮试药物选用。方法对1960例住院患者,采用自身对照,先后使用青霉素及青霉素类药物进行皮内注射。具体每例患者均用双敏方法 :即先用青霉素G钠做皮试,结果为阴性后,再遵医嘱用青霉素类抗生素(以下简称原药)做皮试。结果出现两种情况:A两种药物皮试结果都为阴性;B青霉素G钠皮试结果为阴性,原药皮试结果为阳性。总结B类情况的发生概率。结论建议使用青霉素类抗生素之前,用原药进行皮试更具有科学性,从而能有效降低医疗纠纷发生率。

Objective To explore the selection of penicillin antibiotics before use of skin test drugs. Methods 1960 cases of inpatients, using their own control, has penicillin and penicillin drugs for intradermal injection. Specifically, each patient with Unika method: first with the penicillin G sodium skin test, the result is negative, then prescribed by penicillin antibiotics (hereinafter referred to as the original drug) to do a skin test. The results of two cases: A two drug skin test results were negative; B penicillin G sodium test results were negative, the original skin test results were positive. Summarize the probability of occurrence of Category B cases. Conclusions It is suggested that the skin test with the original drug should be more scientific before using penicillin antibiotics, which can effectively reduce the incidence of medical disputes.