论文部分内容阅读
微转移是指用常规检查方法如影像学、常规病理检查方法难以发现的播散并存活于血循环、淋巴结、骨髓及其他组织器官中的肿瘤细胞。在一些实体瘤的研究中,人们已发现微转移的检出率与患者的预后有密切关系,并可早期诊断肿瘤的复发和远处转移。宫颈癌微转移的检测主要采用免疫组化及PCR技术检测淋巴结、外周血和活检标本中人乳头瘤病毒(HPV)、细胞角蛋白(CK)以及鳞状细胞癌抗原(SCC)的表达。部分研究显示宫颈癌微转移的检测有助于预后判断。
Micro-metastasis refers to tumor cells that are diffused and survive in the blood circulation, lymph nodes, bone marrow and other tissues and organs that are difficult to find by conventional examination methods such as imaging and routine pathological examination. In the study of some solid tumors, it has been found that the detection rate of micrometastasis is closely related to the prognosis of patients, and early diagnosis of tumor recurrence and distant metastasis. The detection of cervical micrometastasis mainly uses immunohistochemistry and PCR to detect the expression of human papillomavirus (HPV), cytokeratin (CK) and squamous cell carcinoma antigen (SCC) in lymph nodes, peripheral blood and biopsy specimens. Some studies show that the detection of cervical cancer micrometastasis contribute to prognosis.