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纤维结素(fibronectine,FNp)为一种高分子量糖蛋白,具多种生物学活性。本文对急性呼吸、循环衰竭患者作血浆FNp测定,以观察其作为判断预后的价值,并研究其与某些凝血因素检测的相互关系。接受检查对象分为3组:①正常对照20例:②急性呼吸衰竭(IRA)53例,包括慢性呼吸衰竭急性失代偿(IRC)28例,急性心源性肺水肿(OAPC)8例,成人呼吸窘迫综合征(SDRA)14例,急性细菌性或病毒性肺炎(PA)13例;③急性循环衰竭(ICA)28例,包括大出血5例,急性腹泻3例,损伤2例,终期心衰4例,心包填塞1例,感染性休克13例。
Fibronectin (FNp) is a high molecular weight glycoprotein with a variety of biological activities. In this paper, plasma FNp was measured in patients with acute respiratory failure and circulatory failure to observe its value as a prognostic value and to investigate its relationship with some coagulation factors. The subjects were divided into three groups: ① 20 cases of normal control: ② 53 cases of acute respiratory failure (IRA), including 28 cases of acute respiratory failure (IRC), 8 cases of acute cardiogenic pulmonary edema (OAPC) 14 cases of adult respiratory distress syndrome (SDRA), 13 cases of acute bacterial or viral pneumonia (PA); ③Acute circulatory failure (ICA) 28 cases, including 5 cases of massive bleeding, 3 cases of acute diarrhea, 2 cases of injury, 4 cases of heart failure, tamponade in 1 case, septic shock in 13 cases.