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对两个含有超抗原T细胞表位的TSST-1交叠肽之Vβ特异性进行了鉴定。结果显示:两合成肽均具备天然TSST-1分子四种人和小鼠Vβ特异性的两种(人Vβ2和小鼠Vβ15)。表明:两合成肽所含有的超抗原T细胞表位是TSST-1特异性的;同时,两合成肽Vβ特异性的一致性,对它们的超抗原T细胞表位可能位于两肽共同序列内的推论无疑是一个有力的佐证
The Vβ specificity of two TSST-1 overlapping peptides containing superantigen T-cell epitopes was identified. The results showed that both of the two synthetic peptides possessed two specificities of Vβ and four of human TSST-1 molecules (human Vβ2 and mouse Vβ15). The results showed that the T-cell superantigen epitope contained in the two synthetic peptides was specific to TSST-1. At the same time, the specificity of the two synthetic peptides, Vβ, was consistent with the fact that their superantigen T-cell epitopes could be located within the two peptide consensus sequence The corollary is undoubtedly a powerful evidence