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目的了解桐乡市20岁以上健康成人麻疹抗体水平,为制定成人麻疹防控策略提供科学数据。方法选择桐乡市20岁~49岁人群,按照自愿原则,采集血清,采用间接酶联免疫法定量检测麻疹Ig G抗体,对抗体阳转率、保护率、抗体浓度水平进行评价。结果共调查1 166人,麻疹抗体阳性率为83.45%、保护率为41.68%、几何平均滴度(GMC)为549.60 IU/L;抗体阳性率、保护率和GMC均随着年龄组上升而上升,差异均有统计学意义(P<0.05)。结论桐乡市成人麻疹易感人群数量庞大,其中20岁~34岁人群麻疹抗体水平较低,不仅自己是高危人群,还导致新生儿体内无母传麻疹保护性抗体,建议在常规麻疹疫苗免费接种基础上,应鼓励育龄妇女接种麻疹疫苗。
Objective To understand the level of measles antibody in healthy adults over the age of 20 in Tongxiang City and provide scientific data for the development of adult measles prevention and control strategies. Methods Choosing 20 to 49 years old population in Tongxiang City. Serum was collected according to the voluntary principle. Ig G antibody of measles was quantitatively detected by indirect enzyme - linked immunosorbent assay (ELISA), and the positive rate of antibody, protective rate and antibody concentration were evaluated. Results A total of 1 166 people were investigated. The positive rate of measles antibody was 83.45%, the protective rate was 41.68% and the geometric mean titer (GMC) was 549.60 IU / L. The antibody positive rate, protective rate and GMC increased with age group , The differences were statistically significant (P <0.05). Conclusion The measles population of measles in Tongxiang City is very large. Among them, the measles antibody level is low in 20-34 years old population. Not only is it high-risk population, it also leads to no measles-protected measles antibody in neonates. Based on this, women of childbearing age should be encouraged to receive measles vaccine.