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目的探讨阴道镜下多点活检联合LEEP术在宫颈上皮内瘤样变(CIN)诊治中的应用价值。方法 60例经阴道镜下多点活检病理诊断为CINⅡ～Ⅲ级患者,应用LEEP术诊治,比较阴道镜下多点活检病理结果与LEEP术后病理结果,观察治愈率和术后并发症发生情况。结果经阴道镜下多点活检病理证实的60例CINⅡ～Ⅲ级患者,LEEP术后经病理诊断相符42例,诊断符合率为70.0%。29例CINⅡ级经LEEP术后病理诊断符合率为79.3%(29/60),31例CINⅢ级经LEEP术后病理诊断符合率为61.3%(31/60);LEEP术后治愈率为93.3%,复发率为1.7%,术后并发症发生率为3.3%。结论阴道镜下多点活检联合LEEP术诊治CINⅡ～Ⅲ级可以提高诊断率,降低误诊率;且LEEP术治疗CINⅡ～Ⅲ级治愈率高,复发率和术后并发症低。
Objective To investigate the value of colposcopy multipoint biopsy combined with LEEP in the diagnosis and treatment of cervical intraepithelial neoplasia (CIN). Methods Sixty patients underwent colposcopic multipoint biopsy were diagnosed as CINⅡ ~ Ⅲ patients. The patients were diagnosed and treated by LEEP. The biopsy result of colposcopy and pathological results of LEEP were compared. The cure rate and incidence of postoperative complications were compared . Results 60 cases of CINⅡ ~ Ⅲ patients confirmed by colposcopy biopsy were pathologically diagnosed by LEEP. The coincidence rate was 70.0%. The coincidence rate of pathological diagnosis of 29 CIN Ⅱ LEEP patients was 79.3% (29/60). The coincidence rate of pathological diagnosis of 31 CIN Ⅲ LEEP patients was 61.3% (31/60). The cure rate of LEEP was 93.3% , The recurrence rate was 1.7% and the incidence of postoperative complications was 3.3%. Conclusions Colposcopic multipoint biopsy combined with LEEP in diagnosis and treatment of CINⅡ ~ Ⅲlevels can improve the diagnosis rate and reduce the misdiagnosis rate. And LEEP technique has the advantages of high cure rate, low recurrence rate and postoperative complications.