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缺血缺氧在组织中产生的内源性腺苷使心搏停止难以逆转。作者用腺苷拮抗剂氨茶硷对阿托品、肾上腺素治疗无效的心搏停止病人进行前瞻性研究。本文报导心搏停止病人15例(男11,女4例,平均71±11岁)在给予2～7mg(3.8±2.2mg)肾上腺素和阿托品2mg治疗无效后,立即快速静脉注射氨茶硷250mg,以观察其疗效。11例病人在快速静注氨茶硷后30秒内出现心脏节律整齐(心率≥75次/分)、血压稳定,因而中止继续进行胸外心脏按压。但其中10例在复苏后4小时～15天内死亡(8例心源性休克,2例缺氧性脑损伤),1例无神经系损伤并发症存活.
Endogenous adenosine produced in tissues during ischemia and hypoxia makes asystole difficult to reverse. The authors use adenosine antagonist aminophylline for atropine, epinephrine ineffective asymptomatic patients for prospective studies. This article reports 15 patients (11 males and 4 females, mean age 71 ± 11 years) with asystole were treated with rapid intravenous injection of 250 mg of aminophylline after treatment with 2 to 7 mg (3.8 ± 2.2 mg) of epinephrine and 2 mg of atropine, , To observe its efficacy. 11 patients with rapid intravenous aminophylline within 30 seconds of heart rhythms (heart rate ≥ 75 beats / min), blood pressure was stable, and thus continue to carry out chest compressions. However, 10 of them died within 4 hours to 15 days after resuscitation (8 cases of cardiogenic shock and 2 cases of hypoxic brain injury) and 1 case of neurological injury without complications.