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呼吸道感染是常见病多发病，而呼吸道感染可导致微生态失调。有报道，宿主的任何病理变化都可作为生态失调的微观环境因素。微观环境对正常微生物群的影响是直接的；而且是主要的。为此，我们对吸烟和被动吸烟者的微生态变化及呼吸道感染患者微生态的变化以及二者之间的关系进行了研究。以进一步探讨吸烟对呼吸道感染患者直接或间接的影响。研究结果表明，吸烟及被动吸烟者患反复呼吸道感染的年发生率明显高于不吸烟者。健康对照组与患者口咽部菌群数相比有显著差异，无论是吸烟还是不吸烟的患者菌群含量均高于健康对照组（Ｐ＜００５）。结果表明，吸烟不仅有害于自身健康，而且危害被动吸烟者，其对呼吸道微生态的影响都是一致的，即可导致微生态失调，从而导致呼吸道疾病
Respiratory infections are common and frequently occurring diseases, and respiratory infections can lead to microecological disorders. It has been reported that any pathological changes in the host can be used as micro-environmental factors of ecological disorders. The effects of the microenvironment on normal microflora are immediate; and predominant. To this end, we studied the microecological changes of smoking and passive smokers and the changes of micro-ecology in patients with respiratory tract infections and the relationship between the two. To further explore the direct and indirect effects of smoking on patients with respiratory tract infections. The results show that smoking and passive smokers have a higher incidence of recurrent respiratory tract infections than non-smokers. There were significant differences in the number of oropharyngeal flora between the healthy control group and the oropharyngeal group, and the content of bacteria in both healthy and non-smokers was higher than that in the healthy control group (P <005). The results showed that smoking not only detrimental to their own health, but also harm passive smokers, their impact on respiratory microecology are the same, that can lead to micro-ecological disorders, leading to respiratory diseases