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败酱科植物缬草用于治疗神经兴奋、胃肠道神经障碍和失眠症有300多年历史,虽然其疗效已被动物试验和临床研究所证实,但对其作用机制仍不十分清楚,曾有报道缬草的二氯甲烷提取物有很强的受体结合作用,本文将其二氯甲烷提取物进一步经硅胶柱层分离,石油醚/丙酮洗脱得六个部位,部位1为烃类,2为倍半萜醇和酮类,3为缬草三酯类,4为IVHD缬草三酯,5为缬草烯酸,6为极性化合物,将这六个部位,
Patriniae plants have been used for the treatment of nerve excitement, gastrointestinal neurological disorders and insomnia for more than 300 years. Although its efficacy has been confirmed by animal experiments and clinical studies, its mechanism of action is still not very clear. It is reported that the methylene chloride extract of Valeriana has a strong receptor binding effect. In this paper, the methylene chloride extract is further separated on a silica gel column and eluted with petroleum ether/acetone at six sites. Site 1 is a hydrocarbon. 2 are sesquiterpene alcohols and ketones, 3 are valerate triesters, 4 is IVHD valeric triester, 5 is valeric acid, 6 is polar compound, these six sites,