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该文旨在评估调强放疗(IMRT)与传统3D适形放疗(RT)相比,是否能够降低下颌骨放射性骨坏死(ORNM)的发生率。作者对2002-2012年间未接受手术的口咽癌患者进行回顾分析。结果,传统RT组145例患者,IMRT组89例患者。2组患者ORNM的发生率无显著差异(11%∶10%,n=16 RT;n=9IMRT;P=1.0)。T4期IMRT组患者ORNM的发生率更高(P=0.007)。结论:IMRT并没有降低ORNM的发生率。
The aim of this study was to evaluate whether IMRT can reduce the incidence of mandibular radiosteel necrosis (ORNM) compared with conventional 3D conformal radiotherapy (RT). The authors conducted a retrospective analysis of patients with oropharyngeal cancer who did not undergo surgery between 2002 and 2012. As a result, there were 145 patients in the RT group and 89 patients in the IMRT group. There was no significant difference in the incidence of ORNM between the 2 groups (11%: 10%, n = 16 RT; n = 9 IMRT; P = 1.0). Patients with T4 IMRT had a higher incidence of ORNM (P = 0.007). Conclusion: IMRT did not reduce the incidence of ORNM.