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目的:观察急性冠状动脉综合征(ACS)患者血清尿酸(UA)、肌钙蛋白I(cTnI)和高敏C反应蛋白(hs-CRP)含量并探讨对其临床预后的预测价值。方法:入选确诊ACS的住院患者592例,收集入院24h内UA、cTnI和hs-CRP的数值,并对患者出院后的心血管事件进行随访,分为心血管事件组和无心血管事件组。结果:UA、cTnI和hs-CRP在2组之间的差异均有统计学意义;校正了年龄、职业、吸烟史、BMI、高血压、糖尿病等相关因素后,血清UA、cTnI和hs-CRP能独立预测ACS患者再发心血管事件。结论:血清UA、cTnI和hs-CRP水平升高与ACS患者的再发心血管事件显著相关,具有较强的预测价值。
OBJECTIVE: To observe the contents of serum uric acid (UA), cTnI and hs-CRP in patients with acute coronary syndrome (ACS) and to evaluate their prognostic value. Methods: A total of 592 hospitalized patients were enrolled in this study. UA, cTnI and hs-CRP were collected within 24 hours after admission. Cardiovascular events were followed up after discharge. Patients were divided into cardiovascular events and non-cardiovascular events. Results: The differences of UA, cTnI and hs-CRP between the two groups were statistically significant. After adjusting for related factors such as age, occupation, smoking history, BMI, hypertension and diabetes, serum UA, cTnI and hs-CRP Can independently predict recurrence of cardiovascular events in patients with ACS. CONCLUSION: Elevated serum levels of UA, cTnI and hs-CRP are significantly associated with recurrent cardiovascular events in patients with ACS and have strong predictive value.