论文部分内容阅读
用丙酮去蛋白法对尿样本进行预处理后,对各实验组及对照组尿中血栓素B_2(TXB_2)6—酮—前列腺素F_(1a)(6—Keto—PGF_(1a))应用放射免疫分析法进行了测定,发现正常对照组(n=103例)TXB_2和6—Keto—PGF_(1a)、的值属于正态分布。肾炎组中二者与正常对照组无显著差异,而肾病组尿6—Keto—PGF_(1a)显著增高,尿TXB_2却显著下降,尿毒症组二者均显著下降。在原发性高血压组中,TXB_2显著增加,尿6—Keto—PGF_(1a)却显著下降。在肝肾综合征中尿TXB_2非常显著地增高,讨论了这些变化的临床意义。
Urine samples were pretreated with acetone-deproteinization method and irradiated with 6-keto-prostaglandin F 1 (1a) (6-Keto-PGF_ (1a)) in each experimental group and control group Immunoassay was performed and the values of TXB_2 and 6-Keto-PGF_ (1a) in normal control group (n = 103) were normal distribution. There was no significant difference between the nephritis group and the normal control group, however, the urinary 6-Keto-PGF_ (1a) increased significantly in the nephropathy group and decreased significantly in the urine TXB_2 group. In the essential hypertension group, TXB 2 increased significantly, urinary 6-Keto-PGF_ (1a) decreased significantly. Urinary TXB 2 increased significantly in hepatorenal syndrome, and the clinical significance of these changes was discussed.