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“硷 C”是从雷公藤根分离得到的一种单体,国内外至今尚未见到有关治疗免疫性疾病的报道。“硷 C”是本所植化室提供。呈无色结晶粉末,熔点167～169℃。使用丙二醇∶吐温80∶水20∶4∶76,配成混悬药液,贮冰箱内备用。实验采用C-(67)BL、615纯种小鼠,均购自北京医学实验动物中心,体重65～110克 Wistar 大白鼠购自本省防疫站。ICR纯种小鼠、18～22g 昆明系杂种小白鼠由我所动物室提供。现将我们对“硷 C”的免疫功能及其毒性实验的观察结果报道于下,供临床应用参考。
“硷C” is a monomer isolated from Tripterygium wilfordii, and it has not been reported at home and abroad regarding the treatment of immune diseases. “硷C” is provided by the Plant’s Planting Room. It is a colorless crystalline powder with a melting point of 167-169°C. The use of propylene glycol: Tween 80: water 20: 4: 76, dubbed a suspension solution, stored in the refrigerator back. The experiment used C-(67) BL, 615 purebred mice, all purchased from the Beijing Medical Experimental Animal Center, weighing 65 to 110 grams. The Wistar rats were purchased from the Provincial Epidemic Prevention Station. ICR purebred mice and 18-22g Kunming hybrid mice were provided by our animal room. We now report the observations of the immune function and its toxicity test of “硷C” for reference in clinical applications.