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为观察家兔输精管结扎后对精子抗原的自身免疫反应与血脂变化的关系,将输精管结扎后7、9个月日本大耳白雄兔20只,随机分为“结扎·胆固醇组”和“结扎·普食组”,另选月龄相近的同种雄兔20只,分为“对照·胆固醇组”和“对照·普食组”。结果表明,在普食条件下,输精管结扎不引起血脂升高,在高脂饲料条件下,输精管结扎组血脂升高较对照组者为著;实验性高脂血症对结扎兔的体液免疫反应没有抑制作用,面对细胞免疫有较弱的抑制作用。
In order to observe the relationship between autoimmune response of sperm antigen and blood lipid changes after rabbit vasectomy, 20 Japanese white-eared rabbits 7 to 9 months after vasectomy were randomly divided into ligation and cholesterol group and ligation. · General food group. Another 20 male rabbits of the same age and age were selected and divided into the “control cholesterol group” and the “control general food group.” The results showed that, under normal diet conditions, vasectomy did not cause the increase of blood lipids. Under high-fat diet conditions, the blood lipid levels in the vasectomy group were higher than those in the control group; the humoral immune response to experimental ligation of rabbits with experimental hyperlipidemia There is no inhibitory effect and there is a weak inhibitory effect on cellular immunity.