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人类运用药物与疾病作斗争,已经历了漫长的年代。随着经验的日益积累,科学的渐趋昌明,药物本身也在不断进化。优良药品不断问世,各种凶险顽疾可望得到治疗,使人们健康明显增进,寿龄逐渐提高。同时,医药工业也形成为一门重要的制造业,创造了巨额财富,培养了技术人才。可是,以现代化技术来衡量:开发新药,时间尚嫌过长,工作量又太巨大。每研制一种新药,平均要经过八千余个化合物的试验。许多合成药物导源于天然药物结构改造,例如吗啡
The long battle for human use of drugs and disease has come a long way. With the accumulation of experience, the science is gradually getting better and the medicine itself is evolving. With the advent of excellent medicines, all kinds of dangerous and stubborn diseases are expected to be treated, people’s health will be obviously improved, and their age will be gradually raised. At the same time, the pharmaceutical industry has also become an important manufacturing industry, creating huge amounts of wealth and cultivating skilled personnel. However, as measured by modern technology, it takes too much time and enormous workload to develop new drugs. Every new drug developed, after an average of more than eight thousand compounds tested. Many synthetic drugs derive from natural drug structural modifications, such as morphine