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疟疾仍然是当前世界上最严重的公共卫生问题之一。据估计,全世界每年有1亿多人患疟疾,有100万十四岁以下的儿童因疟疾死亡。近十年来,由于种种原因,国外室内滞留喷洒灭蚊的面积已大大减少。为控制疟疾,化疗措施在加强。但是,抗氯喹恶性疟原虫的不断出现和扩散,使化疗工作增加了困难。新抗疟药研制工作进展较慢。在今后一段时间内,抗疟运动还是要靠现有的抗疟药。因此,合理使用现有的抗疟药,防止新的抗药性疟原虫出现,已成为人们广泛关注的问题。在大规模进行群众服药的地区,已注意开展疟原虫对抗疟药敏感性的监测。在抗氯喹恶性疟广泛流行的地区,强调要加强灭蚁工作。下面简要介绍国外化疗措施、抗疟药使用和研究的动向。
Malaria remains one of the most serious public health problems in the world at this time. It is estimated that more than 100 million people worldwide suffer from malaria each year, while 1 million children under the age of 14 die from malaria. In the recent ten years, due to various reasons, the area of indoor indoor spraying and mosquito killing has been greatly reduced. Chemotherapy is on the way to controlling malaria. However, the continuous emergence and spread of chloroquine-resistant Plasmodium falciparum have made chemotherapy more difficult. Progress in the development of new anti-malaria drugs is slow. In the coming period, the anti-malaria campaign still depends on existing anti-malaria drugs. Therefore, the rational use of existing anti-malaria drugs to prevent the emergence of new drug-resistant Plasmodium has become a widespread concern. In areas where mass drugging is taking place, monitoring of the susceptibility of malaria parasites to antimalarial drugs has been undertaken. In the areas where chloroquine-resistant falciparum malaria is widespread, emphasis is placed on strengthening ant-killing efforts. The following brief introduction of foreign chemotherapy, antimalarial drug use and research trends.