论文部分内容阅读
目的 观察前列腺素E1 及其脂微球载体治疗高黄疸的乙型肝炎的疗效。方法 随机选血清总胆红素大于正常值5倍的乙型肝炎患者,治疗1组33 例,治疗2 组30 例,对照组28 例。治疗1 组采用国产前列腺素E1,治疗2组采用前列腺素E1 脂微球载体,对照组采用综合药物治疗,观察疗程3周。结果 治疗1 组、治疗2 组与对照组在血清总胆红素、血清丙氨酸转移酶、血清门冬氨酸转移酶、血清白蛋白、凝血酶原活动度的观察指标上有明显差异。结论 前列腺素E1 及脂微球载体在治疗高黄疸的乙型肝炎患者取得较好的疗效,使用国产前列腺素E1 能取得良好的药效经济学。
Objective To observe the curative effect of prostaglandin E1 and its lipid microsphere carrier on hepatitis B with high jaundice. Methods Hepatitis B patients with serum total bilirubin 5 times higher than the normal value were randomly selected. One group had 33 cases, the other two groups had 30 cases and the control group had 28 cases. Treatment group 1 using domestic prostaglandin E1, the treatment group 2 prostaglandin E1 lipid microspheres carrier, the control group with a comprehensive drug treatment, the observation course of 3 weeks. Results There were significant differences in the indexes of activity of total bilirubin, serum alanine aminotransferase, serum aspartate aminotransferase, serum albumin and prothrombin in treatment group 1, treatment 2 and control group. Conclusion Prostaglandin E1 and lipid microspheres carrier in patients with hepatitis B treatment of jaundice achieved good results, the use of domestic prostaglandin E1 can achieve good pharmacodynamics.