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目的:探讨老年不典型NP的感染优势菌、耐药性、致病特点等。方法:对65例老年不典型NP的临床特点、痰菌培养、药敏试验进行回顾性分析。结果:老年人不典型NP基础疾病以肿瘤和慢性肺、脑疾病为主,其首发症状、体征及实验室检查具有不典型性。病原菌以G-杆菌为主,肺炎克雷伯菌占25.7%,并对多种抗生素呈耐药性,头孢哌酮、喹诺酮类的耐药性较低,真菌感染占25.4%,氟康唑对真菌感染有效。结论:早期诊断、根据药敏合理应用抗生素,及时纠正原发病是治疗老年人不典型NP的关键。
Objective: To investigate the dominant bacterium, drug resistance and pathogenic characteristics of atypical NP in the elderly. Methods: The clinical features of 65 elderly atypical NP, sputum culture and susceptibility testing were retrospectively analyzed. Results: The atypical nosocomial diseases of the elderly were mainly tumors and chronic lung and brain diseases. The first signs and symptoms and laboratory tests were atypical. The main pathogens were G-bacteria, Klebsiella pneumoniae accounted for 25.7%, and a variety of antibiotic resistance, cefoperazone, quinolone resistance is low, fungal infections accounted for 25.4%, fluconazole pairs Fungal infection is effective. Conclusion: Early diagnosis, rational use of antibiotics according to susceptibility, timely correction of the primary disease is the treatment of atypical elderly NP key.