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为探讨临床中使用钙制剂抢救链霉素过敏休克病人有良好效果的原因,由被动血凝试验、被动皮肤过敏试验和ELISA法证实,Ca~(++)可以抑制链霉素抗原-抗体的反应。这种抑制作用是通过Ca~(++)链霉素抗原结合,封闭链霉素抗原决定簇来加以实现的。
In order to explore the reasons for the good effect of using calcium preparations in the rescue of patients with streptomycin-induced anaphylactic shock in clinic, it was confirmed by passive hemagglutination test, passive skin allergy test and ELISA that Ca ~ (++) could inhibit streptomycin antigen-antibody reaction. This inhibition is achieved by Ca ~ (++) streptomycin antigen binding, blocking streptomycin epitopes.