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目的分析小儿迁延性及慢性腹泻病的病因、临床症状、治疗及预后。方法随机对住院并诊断为迁延性、慢性腹泻病92例患儿的临床资料进行同顾性分析。结果化验结果大便中乳糖不耐受63例(68.48%),霉菌3例(3.26%),轮状病毒阳性4例(4.35%),菌群失调24例(26.09%)。食物不耐受检测结果显示食物过敏65例(85.53%)。电子结肠镜检查发现炎症性肠病10例(18.87%,溃疡性结肠炎为3例、克罗恩病为7例),过敏性结肠炎为32例(60.38%),非特异性结肠炎为9例(16.98%),息肉合并感染为2例(3.77%)。血清免疫学指标测定结果显示血清免疫球蛋白异常28例(60.87%),CD系列异常11例(30.56%)。针对病因治疗,同时辅以支持疗法和对症治疗,取得了良好的效果。结论迁延性及慢性腹泻病由多种病因引起,发病机制复杂,查找去除病因,对提高治愈率具重要意义。
Objective To analyze the etiology, clinical symptoms, treatment and prognosis of persistent and chronic diarrhea in children. Methods The clinical data of 92 children admitted to hospital and diagnosed as persistent and chronic diarrhea were randomly divided into two groups. Results The test results showed that stool lactose intolerance in 63 cases (68.48%), mold in 3 cases (3.26%), rotavirus positive in 4 cases (4.35%), flora imbalance in 24 cases (26.09%). Food intolerance test results showed that 65 cases of food allergy (85.53%). In colonoscopy, inflammatory bowel disease was found in 10 cases (18.87%, ulcerative colitis in 3 and Crohn’s disease in 7), allergic colitis in 32 (60.38%) and nonspecific colitis Cases (16.98%), polyps infection in 2 cases (3.77%). The result of serum immunological index showed that serum immunoglobulin was abnormal in 28 cases (60.87%) and CD series in 11 cases (30.56%). For the cause of treatment, supplemented by supportive therapy and symptomatic treatment, and achieved good results. Conclusions Persistent and chronic diarrheal diseases are caused by a variety of etiologies. The pathogenesis is complicated and the etiology of etiology is found out. It is of great importance to improve the cure rate.