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目的探讨脱氧核苷酸钠对创伤后肝损伤的治疗作用。方法创伤后肝损害患者54例,随机分为两组。观察组28例,ivgtt,脱氧核苷酸钠100mg,1次/d,连续用7d。对照组26例,ivgtt,维生素C3g、门冬氨酸钾镁20ml,1次/d,连续用7d。结果观察组和对照组丙氨酸转氨酶(ALT)、天冬氨酸转氨酶(AST)、γ-谷氨酰转肽酶(γ-GT)、总胆红素(TB)、直接胆红素(DB)、凝血酶原时间(PT)的显效率分别为42.85%和7.69%,总有效率分别为85.7%和30.77%。观察组疗效明显优于对照组,两组差异有非常显著性意义(P<0.01)。两组血清白蛋白(ALB)比较,差异无显著性意义(P>0.05)。结论脱氧核苷酸钠对创伤后肝损伤有明显疗效,可作为治疗创伤后肝损伤药物。
Objective To investigate the therapeutic effect of deoxynucleotide sodium on post traumatic liver injury. Methods 54 cases of post-traumatic liver injury patients were randomly divided into two groups. The observation group 28 cases, ivgtt, deoxynucleate sodium 100mg, 1 / d, continuous use of 7d. The control group of 26 cases, ivgtt, vitamin C3g, potassium and magnesium aspartate 20ml, 1 / d, continuous with 7d. Results The levels of ALT, AST, γ-GT, total bilirubin (TB), direct bilirubin DB), prothrombin time (PT) were 42.85% and 7.69%, the total effective rate was 85.7% and 30.77% respectively. The observation group was significantly better than the control group, the difference between the two groups was significant (P <0.01). Serum albumin (ALB) between the two groups showed no significant difference (P> 0.05). Conclusion Sodium deoxynucleotide has a significant effect on post-traumatic liver injury and can be used as a drug for the treatment of post-traumatic liver injury.