论文部分内容阅读
目的 探讨慢性肝病患者临床与病理学分级、分期的关系。方法 对 2 0 0例慢性肝病患者的临床表现、血清生化指标与病理学分级、分期进行对比分析。结果 患者的年龄、临床症状及体征积分数与病理分级、分期显著相关(P <0 .0 5 ) ;PLT、RBC、AST、PⅢNP与炎症程度有关 ;PGA指数、PGAA指数、A、A/G与炎症及纤维化均显著相关 ;透明质酸是反映慢性肝病炎症及纤维化严重程度的准确指标 ,血清纤维化指标的优化组合有提高准确性的趋势 ;病毒复制指标与炎症及纤维化未见相关。结论 慢性肝病临床与纤维化病理分级、分期有良好相关性 ,有助于肝纤维化的非创伤性诊断。
Objective To explore the relationship between clinical and pathological grading and staging in patients with chronic liver disease. Methods The clinical manifestations, serum biochemical parameters and pathological grade and staging of 200 chronic liver disease patients were compared. Results The age, clinical symptoms and score of patients were significantly correlated with pathological grade and staging (P <0.05). PLT, RBC, AST and PⅢNP were related to the degree of inflammation. PGA, PGAA, A, A / G And inflammation and fibrosis are significantly related; hyaluronic acid is an accurate indicator of inflammation and fibrosis severity of chronic liver disease, the optimal combination of serum fibrosis indicators have the tendency to improve accuracy; viral replication indicators and inflammation and fibrosis have not seen Related. Conclusion There is a good correlation between clinical and fibrosis pathological grade and staging of chronic liver disease, which is helpful to the noninvasive diagnosis of liver fibrosis.