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目的观察采用非营养性吸吮联合多潘立酮治疗早产儿喂养不耐受(FI)的疗效。方法对发生FI的72例早产儿按随机数学表法分为观察组(37例)和对照组(35例)。对照组均予早产儿常规护理,出现FI后予洗胃、禁食、微量喂养,最终达完全肠内营养;观察组在对照组的综合治疗基础上加用多潘立酮混悬液鼻饲,同时吸吮安慰奶头。观察2组FI消失的时间、每天增加的奶量、体重的增长量及达到肠内营养所需要的时间。结果观察组FI症状消失时间及达到完全肠内营养时间明显短于对照组(P均<0.01),每天增加的奶量明显多于对照组(P<0.01)。2组患儿每天体重增长量比较,差异无统计学意义(P>0.05)。观察组37例患儿使用多潘立酮无不良反应发生。结论非营养性吸吮联合多潘立酮治疗FI效果显著,无不良反应,安全可靠。
Objective To observe the efficacy of non-nutritive sucking combined with domperidone in the treatment of premature infants intolerant (FI). Methods 72 cases of premature infants with FI were divided into observation group (37 cases) and control group (35 cases) according to random number table method. The control group were given routine nursing care of preterm infants, gastric lavage, fasting and micro-feeding appeared after FI, and finally reached full enteral nutrition. The observation group was treated with domperidone suspension nasal feeding on the basis of comprehensive treatment in the control group, Teat. The duration of disappearance of FI, the amount of milk increased daily, the amount of weight gain and the time required for enteral nutrition were observed. Results The disappearance time of FI and complete enteral nutrition in the observation group were significantly shorter than those in the control group (P <0.01). The amount of milk added per day was significantly more than that of the control group (P <0.01). There was no significant difference in the daily weight gain between the two groups (P> 0.05). In the observation group, 37 patients took domperidone without adverse reactions. Conclusion Non-nutritive sucking combined with domperidone treatment of FI significant effect, no adverse reactions, safe and reliable.