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１９９３年１０月至１９９４年２月收集我院４２例经病理证实的宫颈癌患者的宫颈活检标本。鳞癌４１例，其中低分化１１例，中分化３０例；腺癌１例。临床分期Ⅱｂ１２例，Ⅲｂ２８例，Ⅳ期２例。绝经前患者３０例，绝经后１２例。采用酶联雌二醇、孕酮亲和组化法在石蜡切片上进行宫颈癌组织雌激素受体（ＥＲ）、孕激素受体（ＰＲ）半定量检测。标记切片内典型阳性细胞≥１０％为ＥＲ或ＰＲ阳性，≤１０％为ＥＲ或ＰＲ阴性。ＥＲ阳性率为５７．１％，ＰＲ阳性率为６４．３％，中分化鳞癌较低分化鳞癌ＥＲ、ＰＲ阳性率高，但无显著性差异；宫颈癌不同临床分期ＥＲ、ＰＲ阳性率无显著性差异；绝经前后ＥＲ、ＰＲ阳性率亦无显著性差异。本方法简单易行，阳性细胞定位好，可以观察阳性细胞的分布及其与组织类型的关系等优点，有一定的临床实用价值。
October 1993 to February 1994 collected 42 cases of pathologically confirmed cervical cancer patients cervical biopsy specimens. Squamous cell carcinoma in 41 cases, including poorly differentiated in 11 cases, moderately differentiated in 30 cases; adenocarcinoma in 1 case. Clinical stage Ⅱ b12 cases, Ⅲ b28 cases, 2 cases of stage Ⅳ. 30 cases of premenopausal patients, 12 cases after menopause. Semi-quantitative detection of estrogen receptor (ER) and progesterone receptor (PR) in cervical cancer tissues was performed on paraffin sections by enzyme-linked estradiol and progesterone affinity assay. Typical positive cells in labeled sections ≥10% are positive for ER or PR, ≤10% are negative for ER or PR. ER positive rate was 57.1%, PR positive rate was 64.3%, moderately differentiated squamous cell carcinoma of poorly differentiated squamous cell carcinoma ER, PR positive rate, but no significant difference; different clinical stages of cervical cancer ER, PR positive rate No significant difference; before and after menopause ER, PR positive rate also no significant difference. The method is simple and easy to operate, positive cells are located well, the distribution of positive cells can be observed and the relationship between the type of tissue and other advantages, and has certain clinical practical value.