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我们曾证明 ,ＬＰＳ可促进成纤维细胞生长增殖 ,并可促进胞内诱导型一氧化氮合酶的表达[1] 。为探讨成纤维细胞在抗感染免疫中的作用机制 ,本文观察了ＬＰＳ对ＮＩＨ3Ｔ3细胞分泌ＩＬ 6和ＩＬ 8的诱导作用。1 材料和方法1 1 主要试剂 ＬＰＳＥ ｃｏｌｉＯ111:Ｂ4 购自第二军
We have shown that LPS can promote fibroblast growth and proliferation, and promote intracellular inducible nitric oxide synthase expression [1]. In order to investigate the mechanism of fibroblasts in anti-infective immunity, we observed the induction of IL-6 and IL-8 secretion by NIH3T3 cells by LPS. 1 Materials and methods 1 1 The main reagents LPSE coliO111: B4 from the second army