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目的:观察右旋糖酐铁治疗小儿缺铁性贫血的临床疗效。方法:将符合诊断标准的100例患儿随机分为2组,治疗组和对照组各50例。给予治疗组应用右旋糖酐铁,对照组应用硫酸亚铁片,2组治疗均为30天,30天后观察血红蛋白平均细胞体积、血清铁及血清铁蛋白的变化及总有效率。结果:治疗组和对照组患者治疗前后血清检测显示,所有患者治疗后的血清铁蛋白与血红蛋白两种蛋白质指标值均明显升高,治疗前后数值对比差异明显,具有统计学意义(P<0.05)。治疗组和对照组两项指标对比,治疗组上升辐度更大,两组上升福度对比差异明显,具有统计学意义(P<0.05)。结论:右旋糖酐铁相对于硫酸亚铁片在治疗小儿缺贫血上效果更为显著,且无副作用,值得在临床上推广和使用。
Objective: To observe the clinical efficacy of iron dextran in the treatment of iron deficiency anemia in children. Methods: 100 cases meeting the diagnostic criteria were randomly divided into two groups, the treatment group and the control group of 50 cases. The treatment group was given iron dextran and the control group was treated with ferrous sulfate tablets. The two groups were treated for 30 days. After 30 days, the average hemoglobin volume, serum iron and serum ferritin and total effective rate were observed. Results: The serum levels of serum ferritin and hemoglobin in all the patients after treatment were significantly higher than those before treatment (P <0.05), and there was significant difference between the two groups before and after treatment (P <0.05) . The treatment group and the control group two indicators comparison, the treatment group increased greater amplitude, the difference between the two groups was significantly improved, with statistical significance (P <0.05). Conclusion: Iron dextran is more effective than iron sulfate in the treatment of children with anemia, and has no side effects. It is worth to be popularized and used clinically.