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乌头硷类药物常用的有川乌、草乌、附子等。中医多用于风湿骨痛,肾阳不足诸症,其毒性常被人们所忽视,时有中毒病例发生。我院自1985年9月至1990年9月共收治4例,为引起同道注意,现报告如下。例1男, 26岁。煎服含川乌6g中药,半小时后出现手足麻木、发冷,心悸。翌日再服6g,症状加重,四肢活动困难入院。无呕吐、腹泻。查:BP16/8kPa。神清,双瞳缩小,心动过缓,双上肢肌力Ⅱ°,双下肢肌力Ⅰ°~Ⅱ°,肌张力减弱,未引出病理反射。血K~+1.6mmol/L,Na~+140mmol/L,Cl~-100mmol/L,血象、肝、肾功能正常。经洗胃,肌注阿托品总量4mg,大量补液、利尿、补钾,应用地塞米松等治疗。当天输液量4000ml,尿量4400ml,静脉补钾8g,口服补钾7.5g。入院2小时后双瞳为
Aconitine drugs commonly used are Chuanwu, Aconitum, monkshood and so on. Chinese medicine is mostly used for rheumatism and bone pain, kidney yang shortage Zhu Zhu, its toxicity often overlooked by people, when poisoning occurs. Our hospital from September 1985 to September 1990 were treated 4 cases, in order to attract the attention of the same, are as follows. Example 1 male, 26 years old. Decoction containing Chuanwu 6g Chinese medicine, hand, foot numbness after half an hour, chills, palpitations. 6g the next day, symptoms, exacerbations, limb activity difficulties admitted. No vomiting, diarrhea. Check: BP16 / 8kPa. Shen Qing, double-eyes narrowed, bradycardia, upper limb muscle strength Ⅱ °, lower limb muscle strength Ⅰ ° ~ Ⅱ °, weakened muscle tone, did not lead to pathological reflex. Blood K ~ + 1.6mmol / L, Na ~ + 140mmol / L, Cl ~ -100mmol / L, blood, liver and kidney function is normal. After gastric lavage, muscle injection atropine total 4mg, a large number of rehydration, diuretic, potassium, dexamethasone and other treatment. The same day infusion 4000ml, urine output 4400ml, intravenous potassium 8g, oral potassium 7.5g. Double pupil for 2 hours after admission