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随着药代动力学的发展,临床药师与临床医师在医疗实践中应密切协作,将血药浓度监测普遍应用于临床,科学地指导临床医师合理、有效、安全用药,以利彻底改变和纠正盲目用药的状况,且有助于防止药物过量与中毒。除此之外,在发生某些药物急性中毒时,若通过中毒史和临床表现尚难确切肯定诊断时,参考疑似药物的血药浓度测定可以尽快地辅助判断药物中毒的种类和了解中毒的程度,以便及早确立诊断,及时采取相应的急救措施,进行相应的妥善处理。我们将血药浓度监测应用于临床诊疗工作有以下三方面体会:1、保障和指导临床医师合理、有效、安全用药、防止药物过量或中毒。临床治疗中,许多常用药物如:强心甙——洋地黄类各种剂型药品,支气管平滑肌解
With the development of pharmacokinetics, clinical pharmacists and clinicians should collaborate closely in medical practice, and monitor blood concentration generally in clinical and scientific directions to guide clinicians in rational, effective and safe drug use to thoroughly change and correct Blind medication and help prevent overdose and poisoning. In addition, in the event of acute poisoning of some drugs, if through poisoning history and clinical manifestations is still difficult to confirm the exact diagnosis, reference to the determination of plasma concentrations of suspected drugs as soon as possible to help determine the type of drug poisoning and to understand the extent of poisoning , In order to establish the diagnosis as soon as possible, take appropriate emergency measures in time, and properly handle it accordingly. We will blood concentration monitoring application in clinical diagnosis and treatment work has the following three aspects: 1, to protect and guide clinicians reasonable, effective and safe medication to prevent overdose or poisoning. Clinical treatment, many commonly used drugs such as: cardiac glycosides - digitalis various types of drugs, bronchial smooth muscle solution