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本报通讯员、白求恩医科大学校长办公宣 (la0O21)卢维报道该校一院中/加肿瘤中J合刘国津教授、范志民副教授等,首创乳腺癌手术前哨淋巴结定位和活检方法,可决定是否行腋淋巴结清扫。这一技术的应用,可使乳腺癌患者免除腋淋巴结清扫手术之苦。 长期以来,腋淋巴结清扫已成为乳腺癌各种手术的常规部分,但对腋淋巴结清扫是否能局部控制肿瘤并延长患者生存期,仍存在争议。为此,刘国津教授、范志民副教授等在国内首创了乳腺癌术中对淋巴结定位和前哨淋巴结活检技术。该方法是将SIGMA公司生产的专利蓝用蒸馏水稀释为1%的溶液,经高压灭菌后置于冰箱4℃冷藏备用。在患者手术麻醉后抽取4ml专利蓝,在邻近瘤体或活检残腔周围,按顺时针方向在12、3、6、g点处注射到皮下或乳腺实质内(每点lml);以手掌轻轻按压10分钟,待蓝染料充分均匀扩散后,立即行标准乳腺癌改良根治术。标本切除后,通过跟踪和解剖蓝染淋巴管,寻找离癌体中心最近的第一个蓝染淋巴结并将其切除,单独行连续病理切片检查,其余淋巴结同切除标本行常规病理检查。结果发现,33例患者中有30例(91%)找到前哨淋巴结,在其中19例前哨淋巴结阳性者中有n例腋淋巴结呈阳性,8例为阴性,在n例前哨淋巴结阴性者中,有10例腋淋巴结阴性,1例为假阴性,前哨淋巴结预测腋淋?
Correspondent of the newspaper and president of Bethune Medical University Office Propaganda (la0O21) Lu Wei reported that in the first hospital of the university, Professor J Liu and other associate professors such as Professor Liu Guojin and Professor Fan Zhimin in the First Hospital of the University of Hong Kong, have established the first sentinel lymph node location and biopsy method for breast cancer surgery. Axillary lymph node dissection. The application of this technology can eliminate the pain of breast cancer patients with axillary lymph node dissection. For a long time, axillary lymph node dissection has become a routine part of various operations for breast cancer. However, it remains controversial whether axillary lymph node dissection can locally control tumors and prolong the survival of patients. To this end, Professor Liu Guojin and Associate Professor Fan Zhimin have pioneered the use of lymph node localization and sentinel lymph node biopsy techniques in breast cancer surgery in China. The method is to dilute 1% of the patent blue water produced by SIGMA company with distilled water and put it into the refrigerator at 4°C for refrigeration after autoclaving. 4 ml of patent blue was drawn after the patient was anesthetized and injected into the subcutaneous or mammary parenchyma (1ml per point) in the clockwise direction at points 12, 3, 6 and g around the adjacent tumor or biopsy cavity; After a gentle press for 10 minutes, the modified radical mastectomy for breast cancer was performed immediately after the blue dye was fully and uniformly diffused. After the specimens were removed, the blue-stained lymph nodes were traced and dissected to search for the first blue-stained lymph node closest to the center of the cancerous body and removed. The pathological examinations were performed separately. The remaining lymph nodes were resected along with the routine pathological examination. The results showed that 30 out of 33 patients (91%) found sentinel lymph nodes, of which 19 were positive in the axillary lymph nodes and 8 were negative in the sentinel lymph node positive cases. Among the n cases of negative sentinel nodes, there were 10 cases of axillary lymph node were negative, 1 case was false negative, and sentinel lymph node predicts hemorrhoids?