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采用造血祖细胞体外培养与造血生长因子生物活性检测等实验血液学技术，研究三七总皂甙（ＴＳＰＮ），对小鼠粒单系造血祖细胞（ＣＦＵ－ＧＭ）增殖凋控的影响及其机理。结果表明：在有粒单系集落刺激因子（ＧＭ－ＣＳＦ）存在的条件下，ＴＳＰＮ能促进正常或贫血小鼠ＣＦＵ－ＧＭ的集落形成；经ＴＳＰＮ诱导制备的肌条件培养液，Ｌ细胞条件培养液和脾细胞条件培养液能显著提高ＣＦＵ一ＧＭ的集落产率。研究提示，ＴＳＰＮ可能通过诱导机体产生造血凋控因子或协同这些因子促进机体单系血发生。
Using hematopoietic progenitor cell culture in vitro and hematopoietic growth factor bioactivity assays and other experimental hematological techniques to study the effects of Panax notoginseng saponins (TSPN) on the proliferation of mouse hematopoietic progenitor cells (CFU-GM) and their mechanisms. . The results showed that in the presence of granulocyte colony-stimulating factor (GM-CSF), TSPN can promote the colony formation of CFU-GM in normal or anemic mice; muscle conditioned medium prepared by TSPN induction, L cell conditioned culture Liquid and splenocyte conditioned medium can significantly increase the colony yield of CFU-GM. Studies have suggested that TSPN may induce hematopoietic growth factor or synergistically promote the occurrence of single blood in the body through the induction of the body.