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本文报道环孢霉素治疗1例急性皮肌炎Ⅱ型病人。患者,女性,15岁。因四肢肌肉突然疼痛,进行性四肢肌无力住院。全身浮肿眼睑青紫。肌电图示肌炎。左股四头肌活检证实为肌病,肌纤维束周围明显损伤,血管周围淋巴细胞浸润。血沉增速。血清肌酸激酶也升高(稍超出1000u/L),抗核抗体滴度升高(1:640,斑点状荧光型)。发现有循环免疫复合物。血清IgG、IgA、IgM、补体C_3和C_4水平均正常。诊断特发性皮肌炎Ⅱ型,应用甲基强的松龙
This article reports the cyclosporine treatment of 1 case of acute dermatomyositis type Ⅱ patients. Patient, female, 15 years old. Suddenly because of limb pain, progressive limb weakness hospitalized. Edema bruising eyelid. Myoelectric myositis. Left quadriceps biopsy confirmed myopathy, significant damage around the muscle fiber bundle, perivascular lymphocyte infiltration. ESR growth rate. Serum creatine kinase also increased (slightly over 1000u / L), antinuclear antibody titers (1: 640, speckled fluorescence). Found circulating immune complexes. Serum IgG, IgA, IgM, complement C_3 and C_4 levels were normal. Diagnosis of idiopathic dermatomyositis type Ⅱ, the application of methylprednisolone