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本文报道安徽省1986年10月1日～1987年9月30日期间我省29所医院围产儿出生缺陷监测结果。43771名围产儿中,出生缺陷467例,发生率10.67‰;围产儿死亡1600例,死亡率36.55‰。两组性别间均无显著性差异(P>0.05)。81种畸形前五位依次为脑积水、无脑儿、唇腭裂、多指(趾)与足内(外)翻。农村出生缺陷发生率(16.35‰)高于城市(7.37‰),两者有显著性差异(P<0.01)。皖北地区神经管畸形居首位;皖南、皖中则以肢体畸形多见。木文初步探讨了出生缺陷与父母血缘、母亲文化程度低、年龄<20或>35岁、多孕次、产次、双胎等因素的关系。
This article reports the monitoring results of perinatal birth defects in 29 hospitals in Anhui Province from October 1, 1986 to September 30, 1987. Of the 43771 perinatal infants, 467 were born with defects, with a rate of 10.67 ‰; 1600 were perinatal and the mortality rate was 36.55 ‰. There was no significant difference between the two groups (P> 0.05). The top five deformities were hydrocephalus, no brain children, cleft lip and palate, multiple fingers (toes) and feet inside (outside). The incidence of rural birth defects (16.35 ‰) was higher than that of the city (7.37 ‰), with significant difference (P <0.01). Nerve tube deformities in northern Anhui ranked first; Wannan, Anhui is more common to deformities. Muwen discussed the relationship between birth defects and parents’ blood, mother’s education level, age <20 or> 35 years old, multiple pregnancies, parity and twins.