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作者对1例皮肤白细胞碎裂性血管炎患者的不同时期皮疹连续活检,动态观察组织病理变化,进一步证实炎症浸润具有动态变化特性.患者男,66岁.因无症状性皮疹伴腹痛12小时入院.既往有胰岛素依赖性糖尿病.冠状动脉硬化、心律不齐及服用普鲁卡因酰胺而引起的药物性红斑狼疮病史.住院时所用药物有胰岛素、地高辛、华法令、奎尼丁等,其中只有奎尼丁是近3周开始服用的.全身系统性检查无重要阳性体征发现.皮疹为紫癜性丘疹及出血性水疱,主要位于下
The author of a case of skin leukocytoclastic vasculitis patients at different stages of skin rash continuous biopsy, dynamic observation of histopathological changes, and further confirmed that inflammatory infiltration has a dynamic change in patients with male, 66 years old due to asymptomatic rash with abdominal pain 12 hours admission Past history of insulin-dependent diabetes mellitus, coronary atherosclerosis, and drug-induced lupus erythematosus caused by procainamide use of insulin, digoxin, warfarin, quinidine, etc., Only quinidine was taken in the last 3 weeks, and there was no significant positive systemic findings in the systemic examination. The rash is purpuric papules and hemorrhagic blisters,